Includes bibliographies and index.
|Statement||volume editor, C. Sorg.|
|Series||Cytokines ;, v. 1|
|LC Classifications||QR185.8.M3 M53 1989|
|The Physical Object|
|Pagination||viii, 233 p. :|
|Number of Pages||233|
|LC Control Number||88032033|
Additional Physical Format: Online version: Macrophage-derived cell regulatory factors. Basel ; New York: Karger, (OCoLC) Document Type. Full text Full text is available as a scanned copy of the original print version. Get a printable copy (PDF file) of the complete article (K), or click on a page image below to browse page by : J. Taverne. Download PDF: Sorry, we are unable to provide the full text but you may find it at the following location(s): g (external link)Author: J. Taverne. The effects of diffusible macrophage-derived factors on this focal proliferation was investigated using a two-layer culture system which prevented macrophage-lymphocyte contact and permitted B-cell activation to be critically assessed under conditions of extremely low cell densities.
The study was undertaken to evaluate macrophage-derived chemokine (CCL22) levels in the peritoneal fluid (PF) and plasma of patients with ovarian cancer (n = 93) in relation to regulatory T cells (Tregs; n = 75).The peritoneal fluid CCL22 concentrations were significantly higher in epithelial ovarian cancer (EOC) patients than in patients with benign tumors-serous cystadenoma (n = 32). Cytokines Abbreviation: ISSN: (Print) DOI: Recommend this. Further Reading. The aim of this study was to explore further the hypothesis that early stages of normal human hematopoiesis might be coregulated by autocrine/paracrine regulatory loops and by cross-talk among early hematopoietic cells. Highly purified normal human CD34(+) cells . The macrophage-derived product IL-1, (Smith et al., ), together with antigen or mitogen, triggers the T-helper cell to produce IL Only activated cells are responsive to the latter factor which maintains their proliferative capacity (Farrar et al., ).
Cell culture. The human monocytic cell line U (ATCC) was cultured at 8 × 10 5 cells/well in RPMI medium containing 10 % FBS, penicillin (50 U/ml) and streptomycin ( μg/ml) at 37 °C in a 5 % CO 2 atmosphere. Then, 50 nM phorbol myristate acetate (PMA) was used to differentiate U cells for 24 hours prior to the experiments. The production of transformed foci of cells by introduction of fragments of cloned transcripts or genes from tumors also produced a subclass of oncogenes that turned out to be growth factors [c-sis, or PDGF-B chain, and Kaposi’s sarcoma-fibroblast growth factor (kFGF, or FGF-4)]. Most recently, the formation of tumors in vivo after random. Dipeptidyl-peptidase IV (DPP IV/CD26) has a dual function as a regulatory protease and as a binding protein. Its role in the inactivation of bioactive peptides was recognized 20 years ago due to its unique ability to liberate Xaa–Pro or Xaa–Ala dipeptides from the N-terminus of regulatory peptides, but further examples are now emerging from in vitro and vivo experiments. Macrophage-derived exosomes can increase the expression of miR in tumor cells, which reduces the expression of paternally expressed gene 3 (PEG-3), resulting in reduced CD8 + T cell proliferation, cell cytotoxic activity, and IFN-γ level, thereby promoting immune evasion of glioma cells. 96 In addition, in most cases, exosomes derived from.